Final answer:
Cystic Fibrosis is a genetic disease caused by a mutation in the CFTR gene that affects the lungs and digestive system. It leads to the accumulation of thick and sticky mucus in mucus-secreting organs, resulting in recurrent respiratory infections and malabsorption of nutrients.
Step-by-step explanation:
Cystic Fibrosis (CF) is a genetic noninfectious disease caused by a mutation in the CFTR gene. The CFTR protein, which is an integral membrane protein, normally transports chloride ions out of the cell. However, in individuals with CF, the gene is mutated, resulting in the production of a defective channel protein that is not incorporated into the membrane. This leads to the accumulation of thick and sticky mucus in mucus-secreting organs such as the lungs and intestines, causing recurrent respiratory infections and malabsorption of nutrients.