45.0k views
5 votes
Klinefelter's syndrome
*increased risk for gonadal malignancy

User Natarsha
by
6.7k points

1 Answer

6 votes

Final answer:

Klinefelter syndrome is a genetic condition indicated by the 47 XXY chromosomal pattern that increases the risk for gonadal malignancy and comes with various physical and hormonal changes in males.

Step-by-step explanation:

Klinefelter syndrome, with the chromosomal pattern 47 XXY, is a genetic condition that affects male individuals. Typically characterized by physical and hormonal changes such as small testes, enlarged breasts, and reduced body hair, Klinefelter syndrome can also include symptoms like sterility and lower levels of testosterone. In addition to these, there is an increased risk for gonadal malignancy, which means there is a higher chance of developing cancer in the testes compared to the general population. The extra X chromosomes in Klinefelter syndrome, except for one, undergo inactivation, seen as Barr bodies, to balance the genetic dosage. There are more complex variations of Klinefelter syndrome, where an individual may have up to five X chromosomes. Comparatively, Turner syndrome, with an XO genotype, affects phenotypically female individuals with a distinct set of symptoms.

User Stephen Johnson
by
7.4k points