Final answer:
Forceful squeezing when microsampling can result in damage to the vessel wall, leading to compartment syndrome and potential skin breakage.
Step-by-step explanation:
Forceful squeezing when microsampling can result in damage to the vessel wall, leading to further enlargement and increased force. This can cause a painful condition known as compartment syndrome, which occurs when pressure within muscles builds to dangerous levels. In extreme cases, microsampling with excessive force can break the skin.