Final answer:
Naltrexone is most strongly contraindicated in patients with advanced renal disease
Step-by-step explanation:
In patients with advanced renal disease, the medication that is most strongly contraindicated is Naltrexone.
Naltrexone is an opioid receptor antagonist that is primarily used to treat alcohol and opioid dependence. However, it is primarily metabolized by the liver and excreted through the kidneys, so it can accumulate in patients with renal impairment. This can lead to severe side effects, such as hepatotoxicity and nephrotoxicity. Therefore, Naltrexone should be avoided in patients with advanced renal disease.