Final answer:
Donepezil usually doesn't need dose adjustments for hepatic or renal impairment, but caution is advised for severe cases.
Step-by-step explanation:
Donepezil does not typically require dose adjustments in patients with hepatic or renal impairment. This is because the medication has a wide therapeutic index, and its metabolism and clearance are not significantly affected by mild to moderate impairment of these organs. However, as with any medication, clinical judgment should be used when prescribing donepezil to patients with severe hepatic or renal dysfunction, and monitoring for adverse effects is advised.