Final answer:
The sign of opioid overdose is decreased respiratory rate and depth.
Step-by-step explanation:
The sign of opioid overdose is decreased respiratory rate and depth. This means that a person's breathing becomes slow and shallow. Other signs of opioid overdose may include pinpoint pupils, drowsiness, unconsciousness, and seizures. It is important to seek immediate medical help if someone is suspected of experiencing an opioid overdose.