Final answer:
Benzodiazepines should be discouraged in the long-term care setting for therapy of sleep disorders due to adverse effects and risk of dependence and tolerance.
Step-by-step explanation:
The class of medication that should be discouraged in the long-term care setting for therapy of sleep disorders due to risk of adverse effects such as memory impairment, falls, and daytime sleepiness, as well as physiologic tolerance and adverse effects of discontinuation, is E. Benzodiazepines. Benzodiazepines are known to cause cognitive and behavioral adverse effects, and there is a risk of dependence and tolerance with prolonged use. It is important to carefully consider the potential risks and benefits when prescribing medication for sleep disorders.