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Which of the following will be seen in patients on neuroimaging during tic suppression?

A. Increased activity in the frontal cortex
B. Increase activity in globus pallidus
C. Increase activity in the putamen
D. Decrease activity in the caudate nucleus
E. Increase activity in the thalamus

1 Answer

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Final answer:

Increased activity in the globus pallidus, a component of the basal nuclei that controls movement, is typically seen in patients on neuroimaging during tic suppression.

Step-by-step explanation:

Patients undergoing tic suppression typically exhibit increased activity in the globus pallidus on neuroimaging. This is because the globus pallidus is part of the basal nuclei, including the caudate and putamen, which are involved in controlling movement. In the indirect pathway of the basal nuclei, the striatum (composed of the caudate and putamen) projects to the external segment of the globus pallidus and onward through other connections, resulting in increased inhibition of the thalamus and decreased cortical control of movement. Tic suppression is likely to involve modifications in these pathways, leading to the observed changes on neuroimaging.

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