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Which one of the following medications can increase the blood concentration of valproic acid?

A. Acetaminophen
B. Acetylsalicylic acid
C. Cholestyramine
D. Carbamazepine
E. Phenytoin

1 Answer

3 votes

Final answer:

Carbamazepine can increase the blood concentration of valproic acid.

Step-by-step explanation:

The medication carbamazepine can increase the blood concentration of valproic acid.

Valproic acid is primarily metabolized by the liver, and carbamazepine can induce liver enzymes that increase the metabolism of valproic acid, leading to lower blood concentrations.

This interaction is important to consider to ensure appropriate dosing and avoid potential adverse effects.

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