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Which of the following spliceosomal components specifically recognizes and binds to the branch point of the intron during pre-mRNA splicing?

a) U1 snRNP
b) U2 snRNP
c) U4/U6.U5 tri-snRNP
d) U7 snRNP
e) U8 snRNP

User Tony Stark
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1 Answer

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Final answer:

The U2 snRNP is the component of the spliceosome that is responsible for recognizing and binding to the branch point of the intron during pre-mRNA splicing. The correct option is b).

Step-by-step explanation:

The component of the spliceosomal complexes that specifically recognizes and binds to the branch point of the intron during pre-mRNA splicing is the U2 snRNP.

This small nuclear ribonucleoprotein (snRNP) plays a critical role in identifying the branch point sequence, which is essential for the splicing reaction.

Spliceosomes are ribonucleoprotein complexes that orchestrate the precise removal of introns from pre-mRNA. The spliceosome action includes recognition of splice sites, cleaving of the pre-mRNA, removal of the intron in the form of a lariat structure, and subsequent ligation of the exons. Option b) is the correct one.

User Peter Bratton
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