Final answer:
Sudafed PE contains phenylephrine, and Afrin contains oxymetazoline; both are sympathomimetic decongestants used for temporary relief of nasal congestion due to colds or allergies.
Step-by-step explanation:
Sudafed PE and Afrin are both over-the-counter decongestants used to relieve symptoms associated with colds and allergies. Sudafed PE contains the active ingredient phenylephrine, which is a sympathomimetic drug and an α₁-adrenergic agonist. This means it stimulates the adrenergic receptors in the bronchioles of the lungs, causing dilation and helping to clear mucus from the respiratory tract. Afrin, on the other hand, is a nasal spray that contains oxymetazoline, another type of sympathomimetic agent, which provides rapid relief of nasal congestion.
It's important to note that while these medications can be effective for short-term relief, they should not be used for prolonged periods due to the risk of rebound congestion and other potential side effects.