Final answer:
Myasthenia gravis and spinal cord lesions are conditions that decrease the effects of neuromuscular blockers. Other options listed like neomycin, corticosteroids, general anesthetics, and alcohol either do not impact or might potentiate neuromuscular blockage.
Step-by-step explanation:
Select the drug or condition(s) that decrease the effects of neuromuscular blockers. The conditions that can decrease the effects of neuromuscular blockers include:
- Myasthenia gravis: A condition where ACh receptors' function is impaired, causing a lack of sufficient muscle contraction.
- Spinal cord lesions: Can alter neuromuscular transmission and potentially reduce the effectiveness of neuromuscular blockers.
Among the drugs listed, neomycin can potentiate the effects of neuromuscular blockers, not decrease them. Corticosteroids do not typically impact the action of neuromuscular blockers. General anesthetics like isoflurane commonly enhance neuromuscular blockage. Alcohol influence on neuromuscular blockers is not straightforward, and chronic consumption might cause muscle weakness, which should not be confused with a direct decrease in the effects of neuromuscular blockers. Therefore, the correct answers related to the question are Myasthenia gravis and Spinal cord lesions.