Final answer:
Abnormal proliferation of keratinized cells refers to skin cancers affecting keratinocytes, with basal cell carcinoma and squamous cell carcinoma being the most common. Basal cell carcinoma originates from the basal cells and rarely spreads, while squamous cell carcinoma, originating from the stratum spinosum, can be more aggressive and may metastasize if untreated.
Step-by-step explanation:
The abnormal condition of proliferation of keratinized cells commonly refers to specific types of skin cancer that affect the keratinocytes. This can manifest in various forms, including basal cell carcinoma and squamous cell carcinoma.
Basal cell carcinoma is the most prevalent form of skin cancer, originating from the stem cells in the stratum basale layer of the epidermis. It usually appears as a pearly bump and is characterized by its low likelihood of metastasis.
In contrast, squamous cell carcinoma affects the keratinocytes in the stratum spinosum. It is the second most common skin cancer and presents as lesions that can be more aggressive. Although generally localized, it has the potential to metastasize if not treated, typically requiring surgery or radiation for cure.