Final answer:
The primary treatment for an Aspirin/Salicylate overdose is the use of sodium bicarbonate to alkalinize the urine and enhance salicylate excretion.
Step-by-step explanation:
For an Aspirin/Salicylate overdose (OD), the mainstay of treatment involves supportive care and, in some cases, the use of activated charcoal if the patient presents to the medical facility soon after ingestion. However, in the case of significant overdose leading to systemic toxicity, one of the treatments includes the administration of sodium bicarbonate. The use of sodium bicarbonate in aspirin overdose is intended to alkalinize the urine which enhances the excretion of salicylate from the body. Normal saline may be used as well, typically as a fluid replacement to correct dehydration, but it does not have a direct effect on salicylate excretion. Thus, for the reversal of Aspirin/Salicylate OD, Sodium bicarbonate 1 mEq/kg is commonly used, which corresponds to option B).