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Reversal agent for tricyclic antidepressants OD are:

A)Fluid bolus for BP
B)Sodium bicarb 1 mEg/kg slow
C)IVP prepare for seizures
D)None

1 Answer

7 votes

Final answer:

In case of a tricyclic antidepressants overdose, supportive care like fluid bolus for low blood pressure, sodium bicarbonate for cardiac toxicity, and seizure management is important. These interventions are used instead of a specific reversal agent like pralidoxime chloride, which is used for nerve agent poisoning.

Step-by-step explanation:

The question addresses the management of an overdose on tricyclic antidepressants (TCAs). A reversal agent for TCAs is not typically used as one would use pralidoxime chloride for nerve agent poisoning. Instead, the management of a TCA overdose includes supportive care and specific interventions which might include:

  • Fluid bolus for hypotension (low blood pressure)
  • Sodium bicarbonate (1 mEq/kg slowly) for cardiac toxicity, which helps to alleviate the effects of sodium channel blockade caused by TCAs
  • Preparation for potential seizures, which might require intravenous benzodiazepines

However, it's important to note that these appear to be interventions rather than specific reversal agents like 2-PAMCI used for nerve agent poisoning.

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