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38wk LGA infant born by C/S to an A2GDM has dyspnea and grunting. CXR: PERIHILAR STREAKING, AIR TRAMPING (more black). dx? pathophys? RF? prognosis?

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Final answer:

The clinical presentation is suggestive of meconium aspiration syndrome (MAS), where meconium is inhaled into the lungs causing various complications. Treatments often involve airway suction, oxygen, and mechanical ventilation if necessary.

Step-by-step explanation:

A 38-week large for gestational age (LGA) infant born via cesarean section (C/S) to a mother with Type 2 gestational diabetes mellitus (A2GDM) presents with dyspnea and grunting. The chest X-ray shows perihilar streaking and areas of increased translucency indicating air trapping. This clinical presentation is suggestive of meconium aspiration syndrome (MAS). The pathophysiology involves the aspiration of meconium into the lungs, which can lead to airway obstruction, interference with surfactant function, pulmonary inflammation, or hypertension. Risk factors for MAS include fetal distress, maternal drug abuse, maternal hypertension, long labor, or placental insufficiency. The prognosis for infants with MAS varies depending on the severity of the aspiration and the promptness of treatment.

Treatments often involve suctioning of the airways to remove meconium, supplemental oxygen, and in severe cases, mechanical ventilation. Attention to prevention of pulmonary infection is also crucial in the management plan.

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