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3yo male w recurrent swollen, infected lymph nodes in groin and STAPH aureus/MRSA skin ABSCESSES (recurrent). dx? inheritance? patho? how to dx?

User NoodleX
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Final answer:

The child's recurrent infections could indicate a condition like an immunodeficiency or a chronic skin predisposition to infection. Culturing from abscesses, blood tests, and specific pathogen tests are utilized for diagnosis. The causative agent could be staphylococcal bacteria, potentially indicating SSSS or an immunodeficiency.

Step-by-step explanation:

A 3-year-old male with recurrent swollen, infected lymph nodes in the groin and Staphylococcus aureus/MRSA skin abscesses suggests a diagnosis that could be related to several conditions. Recurrent infections of this nature often point to a potential immunodeficiency or a chronic skin condition predisposing to infection. Lymphogranuloma venereum, caused by certain serovars of C. trachomatis, is one possibility, particularly if there is a relevant travel history or exposure, though it tends to be less common in children. More commonly, recurring staphylococcal infections, including MRSA, can suggest underlying conditions like staphylococcal scalded skin syndrome (SSSS) or a primary immunodeficiency.

To diagnose such conditions, medical history, physical examination, and specific laboratory tests are necessary. Culturing for the pathogen from skin abscesses, blood samples, or other bodily fluids can identify the causative agent. Additional tests like polymerase chain reaction (PCR), blood tests to measure white blood cell counts, and tests for specific pathogens (such as passive agglutination for S. aureus or bacitracin susceptibility for Streptococcus pyogenes) are also commonly used.

User Albert Gao
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