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2yo male w/ MULTIPLE ear INFXNS, diarrheal episodes and pneumonias. NO TONSILS seen on exam. dx? hereditary? when does infnx start? results on labs?

User Rok Benko
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1 Answer

6 votes

Final answer:

The condition described suggests a primary immunodeficiency such as agammaglobulinemia, which is often hereditary and characterized by recurrent infections. Diagnosis requires lab testing showing low immunoglobulin levels. Accurate diagnosis and treatment of infections, as shown in the examples, are crucial for recovery.

Step-by-step explanation:

The case presents a 2-year-old male with multiple ear infections, diarrheal episodes, and pneumonias, with absence of tonsils on exam. The description could suggest an underlying immunodeficiency, such as agammaglobulinemia, which is a type of primary immunodeficiency. Agammaglobulinemia is often hereditary and symptoms usually start in the first year of life after the protection from maternal antibodies wanes. Lab results typically show low levels of all immunoglobulin classes, especially IgG, and a lack of B lymphocytes.

The cases included in the question give us a clue about different infections and the methods used to diagnose them. In Tracy's case, bacterial pneumonia caused by Haemophilus influenzae was successfully treated with antibiotics, indicating that timely intervention with appropriate therapy can lead to a full recovery. John's diagnosis of infection with Legionella pneumophila, another bacterial pathogen, was effectively managed with levofloxacin after initial negative tests for influenza. These examples underscore the importance of accurate diagnosis and treatment of infections.

Diarrheal diseases like the one that affected Devin after eating at a restaurant are often caused by bacterial pathogens such as Escherichia coli, which grew on SMAC Agar. Epidemiological data on diseases like salmonellosis shows that oral rehydration therapy is successful in most cases, but antibiotic resistance is a growing concern, especially in severe cases or in immunocompromised patients.

User Roddie
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