Final answer:
The statement regarding CT and multilobar infarction being an absolute contraindication to tPA administration is false. Contraindications to tPA typically involve hemorrhage risk factors, but multilobar infarction alone is not necessarily an absolute contraindication. Each case must be individually assessed.
Step-by-step explanation:
The statement "A CT demonstrating multilobar infarction is an absolute contraindication to tPA administration" is False. Tissue Plasminogen Activator (tPA) can be contraindicated in cases of recent or extensive infarction visible on CT scan, as the risks of hemorrhage increase. Contraindications to tPA typically include evidence of intracranial hemorrhage, recent surgery, active internal bleeding, or signs of massive infarction on imaging, but the presence of multilobar infarction alone does not necessarily preclude the use of tPA. Eligibility for tPA administration should be assessed on a case-by-case basis, considering the size and location of the infarction, time since the onset of stroke symptoms, and the overall clinical picture.