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Bone path:

Sunburst pattern and Codman triangle
Onion skin appearance, osteolytic lesion
Sclerotic, cortical lesion with central lucency

1 Answer

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Final answer:

The question pertains to radiographic signs of bone diseases, including osteosarcoma, Ewing sarcoma, and other conditions like Paget's disease and leprosy. These signs are critical for diagnosis and include the Sunburst pattern, Codman triangle, Onion skin appearance, osteolytic lesions, and sclerotic cortical lesions. It reflects the importance of medical imaging in diagnosing bone pathologies.

Step-by-step explanation:

The student's question refers to various radiographic and clinical signs associated with certain bone diseases and conditions.

  • The Sunburst pattern and Codman triangle are often observed in osteosarcoma, a type of bone cancer.
  • The Onion skin appearance is characteristic of Ewing sarcoma, another bone malignancy that shows layering of new bone growth.
  • Osteolytic lesions refer to areas of bone destruction, commonly seen in multiple myeloma and other bone metastases.
  • A Sclerotic, cortical lesion with central lucency can be indicative of a bone island or enostosis, which is typically a benign condition.

Each of these patterns provides critical information to healthcare professionals about the potential diagnosis and treatment strategies for bone-related ailments. Technologies like computed tomography (CT) and standard radiography are integral in identifying these patterns.

Hypopigmented skin lesions, loss of peripheral nerve function, and loss of extremities mentioned in the question may relate to disorders like leprosy. The intramembranous ossification process is a normal bone development pathway, while conditions like Paget's disease affect bone density and shape, as described in relation to the abnormal curvature of leg bones.

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