Final answer:
Water-soluble nutrients are absorbed directly into the vascular system, while lipid-soluble nutrients are absorbed into the lymphatic system.
Step-by-step explanation:
In contrast to water-soluble nutrients, lipid-soluble nutrients can diffuse through the plasma membrane. Once inside the cell, they are packaged for transport via the base of the cell and then enter the lacteals of the villi to be transported by lymphatic vessels to the systemic circulation via the thoracic duct.
The absorption of most nutrients through the mucosa of the intestinal villi requires active transport fueled by ATP.