Final answer:
The name of the route by which a medication is administered through the skin is the transdermal route.
Step-by-step explanation:
The name of the route by which a medication is administered into the systemic circulation through the skin is the transdermal route. Transdermal delivery involves the use of patches or ointments applied to the skin, allowing the medication to be absorbed into the bloodstream. This route is often used for medications like estrogen, scopolamine, and nitroglycerin.