Question

Suppose that a heterozygous mouse has been bred with four genes of interest: agouti, foxa2, rhoa, and ccrs on two different chromosomes. the agouti phenotype is coded by an autosomal recessive allele, ag. the foxa2 phenotype is coded by an autosomal recessive allele, f. the agouti and foxa2 genes are found in a cis conformation on chromosome 2. on chromosome 9, both the rhoa and ccrs phenotypes are coded by autosomal recessive alleles, c. the notation designates wild-type alleles.

select the haploid recombinant gametes produced by this heterozygous parent:
agf / ag⁺f⁺ rc / r⁺c⁺

a. ag⁺f r⁺c⁺
b. agf⁺ rc⁺
c. ag⁺f⁺ r⁺c
d. ag⁺f⁺ r⁺c⁺

Answer 1

In genetics, predicting recombinant gametes involves understanding allele configurations and possible crossover outcomes. The heterozygous mouse described would produce the recombinant gamete ag⁺f⁺ r⁺c as a result of crossing over. The correct answer is option c.

Step-by-step explanation:

The student's question involves predicting the types of haploid recombinant gametes produced by a heterozygous mouse with specified genotypes at four genes of interest. The mouse in question has four genes across two chromosomes: agouti (ag), foxa2 (f), rhoa (rc), and ccrs (rc), with heterozygous alleles organized in a cis configuration on chromosome 2 (agf / ag⁺f⁺) and on chromosome 9 (rc / r⁺c⁺). The student needs to identify which gametes would be the recombinant products of crossing over events.

These combinations represent the recombinant gametes resulting from crossover events between the genes on each chromosome. The parental allele combinations (agf with rc and ag⁺f⁺ with r⁺c⁺) are not included as they would not be considered recombinant.