Final answer:
During mitosis, a human cell with 46 chromosomes has 92 sister chromatids, each with its own kinetochore, resulting in a total of 92 kinetochores in the cell.
Step-by-step explanation:
During mitosis, a human somatic cell— which contains 46 chromosomes— has its DNA replicated during the S phase of the cell cycle. This results in each chromosome being composed of two identical copies called sister chromatids, held together by a centromere.
Hence, there are 92 chromatids in total. For the purposes of cell division, each sister chromatid is equipped with its own kinetochore, a structure that facilitates attachment to the spindle fibers necessary to pull the chromatids apart during anaphase.
Therefore, considering each of the 92 sister chromatids has a kinetochore, there are 92 kinetochores present in a human cell during mitosis. This is crucial for the accurate segregation of chromosomes into the two daughter cells, ensuring that each new cell receives the correct number of chromosomes.