Final answer:
The effectiveness of the new medicine will not be able to be determined because the doctor did not have a different random sample of patients take the original medication.
Step-by-step explanation:
The true statement about the design of this experiment is option 3: The effectiveness of the new medicine will not be able to be determined because the doctor did not have a different random sample of patients take the original medication.
This statement highlights the absence of a control group that received the original medication, which would enable a comparison to be made between the effects of the new medicine and the effects of the original medication.
Without a control group, it is impossible to determine whether any observed effects are due to the new medicine or other factors.