Final answer:
Propylthiouracil would not cause goiter formation in a thyroidectomized rat since there is no thyroid tissue remaining to enlarge. Goiter is typically associated with hypothyroidism, characterized by symptoms like weight gain and cold sensitivity.
Step-by-step explanation:
Propylthiouracil injections, which inhibit the production of thyroid hormones T3 and T4, would result in the formation of a goiter in the thyroidectomized rat. Generally, a goiter is caused by the body's attempt to compensate for an insufficient production of T3 and T4 due to iodine deficiency by overproducing Thyroid-Stimulating Hormone (TSH).
However, with the thyroid gland removed in a thyroidectomized rat, the usual effects of propylthiouracil, or the overproduction of TSH, would not result in a goiter because there is no thyroid tissue left to swell. In such a case, propylthiouracil injections would not cause goiter formation in the thyroidectomized rat. Normally, symptoms one would expect from goiter include hypothyroidism, resulting in weight gain, cold sensitivity, and reduced mental activity.