Final answer:
The statement is true; all transport vesicles in the cell require v-SNARE proteins for binding to complementary T-SNARE proteins on target membranes, which is necessary for vesicle fusion and content delivery.
Step-by-step explanation:
The statement that all transport vesicles in the cell must have a v-SNARE protein in their membrane is true. The v-SNARE (vesicle-SNARE) proteins are essential components of the cellular transport machinery. When a vesicle buds off from the trans-Golgi stack, it incorporates v-SNARE proteins into its membrane. These proteins are crucial for the vesicle to bind complementary T-SNARE (target-SNARE) proteins that reside on the membranes of target compartments such as the plasma membrane or other organelles. The binding of v-SNAREs to T-SNAREs facilitates the fusion of the vesicle with the target membrane, allowing the delivery of vesicular contents to the appropriate location within the cell.