Final answer:
Immunoglobulin superfamily members bind to integrins and selectins, with integrins engaging in tissue development and repair, and selectins involved in blood clot formation. IgM and IgG antibodies bind to antigens and through adhesion, contribute to immune responses such as complement activation and pathogen agglutination.
Step-by-step explanation:
Some members of the immunoglobulin superfamily bind to adhesion molecules known as Integrins and Selectins.
Integrins are heterodimeric transmembrane receptors that bind to various extracellular matrix proteins, including fibronectin, laminin, collagens, and many others. They are critical for stimulating tissue development at implant/tissue interfaces and play a role in cell attachment to biomaterial scaffolds in tissue engineering.
Selectins participate in blood clotting by allowing platelets to recognize and bind specific receptors on other platelets, aiding the formation of a clot. In the immune response, IgM and IgG antibodies can bind to antigens, and through their adhesion properties, facilitate processes like complement activation, cell lysis, and agglutination, where pathogens are clumped together making them easier to be filtered from the blood or destroyed by phagocytes.