Final answer:
Signaling molecules in paracrine and autocrine signaling move by diffusion through the extracellular matrix for local communication, unlike endocrine signals which use the circulatory system for long-distance signaling.
Step-by-step explanation:
Signaling molecules involved in paracrine and autocrine signaling travel by diffusion. In paracrine signaling, the signals act locally between cells that are close together, moving through the extracellular matrix by diffusion. These signals generally elicit rapid responses and their effects are quickly terminated to remain localized. Autocrine signaling occurs when the signaling cell targets itself, also involving diffusion of the signals. However, the long-range endocrine signaling employs the circulatory system to transport signals, usually hormones, across the body.
Signaling molecules involved in paracrine and autocrine signaling travel by diffusion through the extracellular matrix. These molecules act locally between cells that are close together. Paracrine signaling elicits quick responses that last only a short period of time.