Final answer:
Histones are not associated with prokaryotic genomes. In prokaryotes, DNA is organized as a circular chromosome within the nucleoid region and is compacted by supercoiling, not by wrapping around histones as in eukaryotes.
Step-by-step explanation:
The student's question is related to the features associated with prokaryotic genomes. Among the options given, histones are not associated with prokaryotic genomes. Prokaryotic cells, such as bacteria and archaea, have a circular chromosome and lack a nuclear membrane, whereas histones are the proteins around which eukaryotic DNA is wound to form nucleosomes, a feature not present in prokaryotes.
Prokaryotic DNA is located in the nucleoid region of the cell and often includes plasmids, which are shorter circular DNA molecules. The DNA within prokaryotes is compacted by supercoiling, assisted by enzymes such as DNA gyrase, rather than being wound around histones.