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A 62-year-old woman with a history of asthma and alcoholism is beginning drug therapy for Alzheimer's disease. The physician has ordered an acetylcholinesterase enzyme inhibitor. Which part of the health history data is most important for the nurse to consider?

-age.
-gender.
-history of alcoholism.
-history of asthma.

1 Answer

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Final answer:

The most important aspect of the patient's health history to consider is her history of asthma. This is due to the possibility that an acetylcholinesterase inhibitor could exacerbate asthma symptoms, which is a critical health risk to manage.

Step-by-step explanation:

When considering drug therapy for Alzheimer's disease with an acetylcholinesterase enzyme inhibitor in a 62-year-old woman with a history of asthma and alcoholism, the most important part of her health history to consider is her history of asthma. Acetylcholinesterase inhibitors can cause bronchoconstriction, which is a potential concern for an asthmatic patient due to her pre-existing respiratory condition. This can exacerbate her asthma symptoms, creating additional health complications. While age, gender, and history of alcoholism are also relevant, the immediate impact of the drug on her respiratory system is the most critical to monitor.

Acetylcholinesterase inhibitors are a class of drugs used to treat Alzheimer's disease. They work by blocking the enzyme acetylcholinesterase, leading to increased levels of the neurotransmitter acetylcholine in the brain. This effect can enhance communication between neurons and may help maintain cognitive function for a longer period. However, increased acetylcholine can also affect other areas of the body and worsen asthma symptoms.

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