Final answer:
During the 2008-2009 influenza season, both influenza A H3N2 and novel influenza A H1N1 were resistant to neuraminidase inhibitors. These drugs can shorten the course of the disease by preventing the release of the virus from infected cells.
Step-by-step explanation:
The subject of this question is Biology. The question asks about the resistance of influenza A H3N2 and novel influenza A H1N1 at the end of the 2008-2009 influenza season.
During the 2008-2009 influenza season, 100% of the influenza A H3N2 and novel influenza A H1N1 were resistant to the three neuraminidase inhibitors: zanamivir, oseltamivir, and peramivir. These drugs, when taken at the onset of symptoms, can shorten the course of the disease by inhibiting the release of the influenza virus from infected cells.
Research and surveillance are ongoing to monitor and understand the resistance patterns of influenza viruses and to develop effective vaccines and antiviral treatments.