Final answer:
Canals of Lambert are found in the respiratory bronchioles and alveolar ducts, providing a collateral pathway for airflow. Clara cells, or club cells, are specialized cells located in the terminal and respiratory bronchioles, involved in detoxifying substances, secreting surfactant components, and preventing inflammation.
Step-by-step explanation:
The canals of Lambert are microscopic channels that can be found at the level of the respiratory bronchioles and alveolar ducts. They serve as connections between the terminal bronchioles and adjacent alveoli, providing a collateral pathway for airflow in the lung. This can be especially important in cases where the bronchioles are obstructed. The canals of Lambert can help air reach parts of the lung that would otherwise be inaccessible due to blockages in the larger airways.
On the other hand, Clara cells (also known as club cells) are non-ciliated, dome-shaped cells that line the epithelium of the bronchioles - particularly the terminal and respiratory bronchioles. These cells are important for detoxifying harmful substances, secreting components of surfactant, and preventing bronchiolar inflammation. Clara cells may also serve as progenitor cells to regenerate the bronchiolar epithelium.