Final answer:
The crop that did not originate in the New World and thus is not native to the Americas is wheat. Maize, tobacco, and potato were all domesticated in the Americas, while wheat was domesticated in the Middle East.
Step-by-step explanation:
The crop that did not originate in the New World among those listed is wheat. Wheat's history dates back to the Fertile Crescent in the Middle East, a region that is often considered the birthplace of agriculture. Unlike tobacco, maize (corn), and potato, all of which were domesticated in the Americas, wheat was not native to this part of the world. These New World crops were then spread to Europe and other parts of the globe following the Colombian Exchange which began after 1492.