Final answer:
The request to load, change, or delete ISG items must be justified in writing by an Information Systems Manager or System Administrator. They must document reasons for the change and ensure adherence to internal controls, regulations, and create an audit trail.
Step-by-step explanation:
The individual who must justify in writing the request to load, change, or delete Information System General (ISG) items is typically a person with direct responsibility for the system or data. This would usually be an Information Systems Manager or a designated System Administrator within an organization. They are responsible for ensuring that any modifications to the system adhere to internal controls and policy standards, as well as any applicable legal or regulatory requirements. Whenever changes are proposed to an ISG, it's crucial that they are thoroughly documented to prevent unauthorized or inadvertent alterations that could compromise the integrity or security of the system. The justification must be clear, outlining the reasons for the change and the expected impact. It should also be approved and recorded for audit purposes, maintaining a clear audit trail for accountability.