Final answer:
The Indians' lives changed due to Westward Expansion through forced relocation, loss of land and resources, and exposure to new diseases.
Step-by-step explanation:
The lives of Indians were significantly impacted by Westward Expansion in several ways. One of the primary changes was forced relocation, as Native Americans were pushed off their ancestral lands to make way for new settlers. This often led to violent confrontations and the loss of traditional ways of living. Secondly, there was a substantial loss of land and resources, which disrupted the Indians' ability to sustain their communities as they had for generations. Thirdly, exposure to new diseases brought by European settlers had devastating effects on the native populations, as they had little to no immunity to these illnesses.