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Which Ig(s) is almost always cell associated on the surface of b lymphocytes?

a. IgD
b. IgA
c. IgM

User Jirennor
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1 Answer

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Final answer:

IgM and IgD are the immunoglobulins typically found on the surface of B lymphocytes, with IgM being the predominant one involved in the body's initial immune response.

Step-by-step explanation:

The immunoglobulins (Ig) that are almost always cell associated on the surface of B lymphocytes are IgM and IgD. Naïve B cells express IgM in a monomeric membrane-bound form which acts as the antigen-binding receptor.

Together with IgM, IgD is also found on the surface of B cells, however, it is present only in trace amounts in the serum and is mainly important for antigen recognition and B cell maturation. IgM, on the other hand, is secreted by plasma cells in a pentameric form after its initial response as a monomer on naive B cells, making it essential in the body's first line of defense against infections.

User Obby
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