Final answer:
A P20 micropipette set to draw 2 microliters will require more pressure than when set to 20 microliters, since a smaller volume requires higher pressure for precision, akin to Boyle's Law.
Step-by-step explanation:
The question asks about the pressure required to draw liquid using a micropipette set to different volumes. Using the principle that pressure (P) and volume (V) are inversely related as per Boyle's Law, we can deduce that drawing a smaller volume will require a higher pressure.
When using a P20 micropipette, which is designed for volumes between 2-20 μl, setting it to draw 2 microliters will require more precision and a potentially higher pressure compared to setting it to draw 20 microliters. This is similar to inflating a smaller balloon compared to a larger one; the smaller the balloon, the more pressure is needed to inflate it.
To summarize, the P20 set to 2 microliters will require more pressure to draw the desired amount of liquid than when it is set to draw 20 microliters.