Final answer:
Receptor-mediated endocytosis activates naive CD8+ T cells, which become cytotoxic T lymphocytes (CTLs) responsible for killing infected cells, while CD4+ T cells become helper T cells aiding in immune response.
Step-by-step explanation:
In the process of receptor-mediated endocytosis, a type of naive T cell known as CD8+ is activated. Naive T cells express either CD4 or CD8 molecules on their surface. Naive CD4+ T cells bind to MHC II molecules on antigen-presenting cells (APCs) and become helper T (TH) lymphocytes. Conversely, naive CD8+ T cells engage MHC I molecules on APCs and differentiate into cytotoxic T lymphocytes (CTLs), which are responsible for directly killing infected cells. This process is a part of the cell-mediated immune response. The humoral immune response, in contrast, involves activated B cells that produce antibodies.