Final answer:
The Framers had disagreements on taxation and commerce, which were resolved through the Three-Fifths Compromise. They also had disagreements on state sovereignty, which were resolved through the Supremacy Clause.
Step-by-step explanation:
The Framers of the Constitution had several disagreements about the powers of Congress. One of the major disagreements was on taxation and commerce. Some states were concerned that Congress would have too much power to tax their export crops, so a compromise was reached known as the Three-Fifths Compromise, which allowed northern states to tax imports but not exports.
Another disagreement was on state sovereignty. The Framers resolved this disagreement through the Supremacy Clause, which established that the Constitution and laws passed by Congress would be the supreme law of the land, overriding any conflicting state laws.