Final answer:
The observation that stools are less fatty and decreased in frequency is the best indicator that pancrelipase (Viokase) treatment for chronic pancreatitis is effective.
Step-by-step explanation:
Effective Treatment Indicators for Chronic Pancreatitis with Pancrelipase
When assessing the effectiveness of pancrelipase (Viokase) treatment for chronic pancreatitis, the most relevant observational factor is the change in stools. Pancrelipase aids in the digestion of fats due to the presence of pancreatic lipase, which is crucial for breaking down triglycerides into fatty acids and monoglyceride molecules. A patient with chronic pancreatitis may have difficulty in lipid digestion, which may result in the passing of fatty and frequent stools. Therefore, the observation that is the best indicator of effective pancrelipase treatment is that stools are less fatty and decreased in frequency (option 4). An improvement in appetite (option 2) may also be seen but is less specific than stool changes; options 1 and 3 are generally not associated with the treatment's effectiveness.
For Leigh Ann, receiving treatment for chronic pancreatitis, noting her stool characteristics is essential in determining the efficacy of pancrelipase. If the stools become less greasy and there is a reduction in the number of bowel movements, this indicates that the pancrelipase is functioning well, aiding her body in lipid metabolism and proper digestion of fats due to the enhanced action of pancreatic lipase.