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What are all the places we need/use NADPH and which pathway produces it?

User Bhullnatik
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Final answer:

NADPH is an energy carrier molecule produced in the light reactions of photosynthesis and used in the Calvin cycle. It is vital for many cellular processes including fatty acid and cholesterol synthesis, as well as in antioxidative and detoxification pathways.

Step-by-step explanation:

NADPH (Nicotinamide adenine dinucleotide phosphate) is a crucial energy carrier molecule produced during the light reactions of photosynthesis. This energy-rich molecule is utilized in the Calvin cycle or the light-independent reactions where it plays a significant role in the reduction of 3-phosphoglycerate (3-PGA) to glyceraldehyde 3-phosphate (G3P). Specifically, NADPH provides the reducing power to add high-energy electrons to the carbon compounds in the Calvin cycle.

NADPH is not only important in photosynthesis but is also a key player in various cellular processes including fatty acid and cholesterol synthesis, as well as in the detoxification of reactive oxygen species within cells. It is involved in the pentose phosphate pathway, a pathway parallel to glycolysis, which is primarily responsible for generating NADPH and ribose 5-phosphate, another precursor vital for nucleotide synthesis.

To summarize, NADPH is fundamental to many biosynthetic, detoxification, and antioxidative pathways. It is produced in the light-dependent reactions of photosynthesis and is essential for driving the synthesis of carbohydrates in the light-independent reactions, among other uses.

User Octavian Niculescu
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