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Is ATGL on or off in a fasted state? How is it regulated?

User Obtice
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Final answer:

In the postabsorptive state, ATGL is turned on to break down stored triglycerides into fatty acids. This process helps provide energy for the body during fasting. ATGL is regulated by hormones, specifically glucagon.

Step-by-step explanation:

In the postabsorptive state, ATGL (adipose triglyceride lipase) is turned on to break down stored triglycerides into fatty acids and glycerol. This process helps provide energy for the body during fasting. ATGL is primarily regulated by hormones in the body.

When blood glucose levels decrease during the postabsorptive state, the hormone glucagon is released from the pancreas. Glucagon acts upon adipose tissue to activate ATGL and promote the breakdown of triglycerides into fatty acids. This allows the fatty acids to be used as an energy source by the body.

User VeroneseComS
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