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In most cases, in a full-length clone, translation starts at what specific sequence or region?

User Jwknz
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Final answer:

Translation in eukaryotic cells generally starts at the AUG start codon, which is identified by the ribosome scanning from the 7-methylguanosine cap at the 5' end of the mRNA, following Kozak's rules for consensus sequence.

Step-by-step explanation:

In most full-length clones, translation generally starts at the AUG start codon. For eukaryotic cells, the process begins with the ribosome recognizing the 7-methylguanosine cap at the 5' end of the mRNA.

The ribosome then scans for the AUG start codon, guided by Kozak's rules which specify that the consensus sequence 5'-gccRccAUGG-3' indicated by R being a purine (A or G), should be around the AUG start codon for higher translation efficiency. This consensus sequence helps in distinguishing the correct translation start codon.

User Lejlek
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