Question

What are the definitions of "Affinity" and "Intrinsic Activity"?

A) Affinity: Attraction or kinship; Intrinsic Activity: Essential or inherent behavior
B) Affinity: Hostility or aversion; Intrinsic Activity: Extrinsic or superficial engagement
C) Affinity: Indifference or detachment; Intrinsic Activity: External or artificial performance
D) Affinity: Association or similarity; Intrinsic Activity: Internal or inherent effectiveness

Answer 1

Affinity refers to the strength of the interaction between an antibody and its antigen, with higher affinity indicating stronger, more stable binding. Intrinsic activity is the extent to which a drug can elicit a response upon binding to a receptor, with a high intrinsic activity leading to a strong response.

Step-by-step explanation:

The correct definition for Affinity and Intrinsic Activity from the provided options is D) Affinity: Association or similarity; Intrinsic Activity: Internal or inherent effectiveness. In the context of immunology and pharmacology, affinity refers to the strength of the interaction between an antibody and its antigen or a drug and its receptor. A higher affinity indicates a stronger and more stable binding. Each IgG antigen-binding site typically has a high affinity for its respective target antigen. The concept of intrinsic activity pertains to the inherent ability of a drug to elicit a response when it binds to a receptor. A drug with high intrinsic activity will produce a strong effect even at low concentrations.