Final answer:
Isaac Hull was the captain of the ship in 1812, not the other Isaacs mentioned, such as Isaac Newton, who is known for his contributions to science.
Step-by-step explanation:
The individual who captained a significant ship in 1812, as mentioned in the question, is Isaac Hull. The other individuals listed, including Isaac Newton, Isaac Smith, and Isaac Davis, do not fit the historical context of captaining a ship in 1812. Isaac Newton, for example, was a prominent figure in the Scientific Revolution known for his work on the laws of motion, gravity, optics, and mathematics, and not for captaining a ship during that period.