Final answer:
Issuing a film in limited release in first-run theaters in major cities allows filmmakers to assess audience reactions and evaluate the film's potential commercial success.
Step-by-step explanation:
Issuing a film in limited release in first-run theaters in major cities is typically used to discern whether it will find favor with moviegoing audiences. This limited release strategy allows filmmakers to gauge audience reactions and evaluate the potential commercial success of the film before expanding its release to more markets. It helps the studio assess the film's performance and make any necessary adjustments or marketing decisions based on audience feedback.