Final answer:
John Young was the pilot from Apollo 16 who later commanded the first space shuttle flight STS-1.
Step-by-step explanation:
The pilot who went to the moon on Apollo 16 and also flew the space shuttle is not distinguished in the provided information, as there is an inconsistency. The astronauts who went to the moon on Apollo 16 were John Young, Charles Duke, and Ken Mattingly; yet Ken Mattingly did not land on the moon but remained in orbit. John Young is the astronaut from Apollo 16 who later flew on the space shuttle, becoming the ninth person to walk on the moon in April 1972 on Apollo 16 and later commanding the first space shuttle flight STS-1 in April 1981. Young is notable for his participation in both of these significant moments in the history of space exploration.