Final answer:
In the fed state, Lipoprotein Lipase (LPL) is activated in adipose and muscle tissues due to the presence of insulin, which leads to increased lipid uptake and storage in these tissues.B) Activated
Step-by-step explanation:
In the fed state, Lipoprotein Lipase (LPL) is activated in adipose and muscle tissues. LPL is essential for the proper metabolism of lipids by enabling the breakdown of triglycerides into free fatty acids and glycerol that can be absorbed by the tissues. In the fed state, the presence of insulin stimulates the production of LPL, thereby facilitating the uptake of triglycerides from the bloodstream into adipose and muscle tissues for use as energy or storage. Conversely, during fasting, the decreased levels of insulin and increased levels of hormones like glucagon lead to inactivation of LPL, promoting the release of free fatty acids back into the bloodstream.
Regulation of enzymes like LPL is crucial for maintaining energy homeostasis in the body. Inhibitors would decrease enzyme activity, while activators increase it. Since insulin acts as an activator of LPL, we can conclude that in response to a meal (when insulin levels are high), LPL becomes more active in adipose and muscle tissues, supporting lipid storage and energy use.