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A 33-year-old male is brought in because he tried to light his body on fire. He tearfully states that satan is trying to freeze his body. In the past winter, he never went outside for this reason and describes feeling sad to a point that he wanted to kill himself. Further questioning reveals that he had a few similar episodes over the last 10 years. When he was treated with risperidone and sertraline, his mood symptoms resolves but his delusions persisted. Think:

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Final answer:

Schizophrenia is a serious and often debilitating mental illness that affects one percent of people in the US. It causes a range of symptoms including hallucinations, delusions, difficulty thinking, and problems with social interaction. Treatment typically involves antipsychotic medication, although it is not a cure.

Step-by-step explanation:

Schizophrenia is a serious and often debilitating mental illness affecting one percent of people in the United States. Symptoms of the disease include the inability to differentiate between reality and imagination, inappropriate and unregulated emotional responses, difficulty thinking, and problems with social situations. People with schizophrenia can suffer from hallucinations and hear voices; they may also suffer from delusions. Patients also have so-called "negative" symptoms like a flattened emotional state, loss of pleasure, and loss of basic drives. Many schizophrenic patients are diagnosed in their late adolescence or early 20s. The development of schizophrenia is thought to involve malfunctioning dopaminergic neurons and may also involve problems with glutamate signaling. Treatment for the disease usually requires antipsychotic medications that work by blocking dopamine receptors and decreasing dopamine neurotransmission in the brain. This decrease in dopamine can cause Parkinson's disease-like symptoms in some patients. While some classes of antipsychotics can be quite effective at treating the disease, they are not a cure, and most patients must remain medicated for the rest of their lives.

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